Lakers vs. Spurs Predictions, Odds & Stats – Dec. 10

The Los Angeles Lakers (17-6) play the San Antonio Spurs (16-7) as 7-point favorites on Wednesday, December 10, 2025 at 10 p.m. ET on Amazon Prime Video and SportsNet LA.

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Lakers vs. Spurs Predictions for Wednesday

Our computer projection model for this game expects a final score of Lakers 118, Spurs 117.

  • Moneyline Pick: Lakers (-282)
  • Total Pick: Under 242 (computer predicts 234.6 points)
  • Pick ATS: Spurs (+7)

Recent Lakers vs. Spurs Matchups

Lakers vs Spurs (Recent Matchups)
Date Favorite Spread Total Favorite Moneyline Underdog Moneyline Result
11/5/2025 Spurs -1.5 227.5 -121 +101 118-116 LAL
3/17/2025 Lakers -9.5 230.5 -444 +341 125-109 LAL
1/13/2025 Lakers -4 221.5 -186 +154 126-102 SA
11/27/2024 Lakers -1.5 227.5 -134 +112 119-101 LAL
11/15/2024 Lakers -2.5 228 -138 +117 120-115 LAL

Lakers 2025-26 Betting Trends

  • Los Angeles is 14-9-0 against the spread this season.
  • The Lakers are 3-3 against the spread when favored by 7 points or more this season.
  • A total of 16 of Los Angeles' 23 games with a set total have hit the over (69.6%).
  • This season, the Lakers have been favored 12 times and won 10, or 83.3%, of those games.
  • Los Angeles has been at least a -282 moneyline favorite six times this season and won all of those games.

Spurs 2025-26 Betting Trends

  • So far this year, San Antonio has put together a 10-11-2 record against the spread.
  • The Spurs are 2-0 against the spread so far when playing as at least 7-point underdogs.
  • San Antonio's games have hit the over 13 out of 23 times (56.5%).
  • The Spurs have put together a 6-3 record in games they were the underdog on the moneyline (winning 66.7% of those games).
  • San Antonio has won all two games it has played as a moneyline underdog with odds of +227 or longer.

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Lakers vs. Spurs Injury Report

Lakers

Lakers:

Maxi Kleber: Questionable (Back)

Spurs

Spurs:

Jordan McLaughlin: Questionable (Hamstring),

Victor Wembanyama: Out (Calf),

Carter Bryant: Questionable (Illness)

Lakers vs. Spurs Game Time and TV Channel

  • Game day: Wednesday, December 10, 2025
  • Game time: 10 p.m. ET
  • TV channel: Amazon Prime Video and SportsNet LA
  • Location: Los Angeles, California
  • Arena: Crypto.com Arena

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